This pistol packs a powerful punch, and even though it crosses your path pretty early in the main storyline, it remains relevant throughout the game. What is the best legendary weapon in Fallout 4? Due to the potentially high amount of radiation poisoning the gamma gun can do (upwards of 400 rads with a combination of Nuclear Physicist, mods and irradiated legendary prefix), this gun can be highly effective against tough enemies especially on high difficulties (since radiation poisoning is unaffected by.
